Abstract: Since its launch in 2009, NASA's Kepler Mission has transformed our knowledge of exoplanetary system demographics. Kepler's primary mission goal-- to quantify the occurrence rate of habitable zone Earth-size planets around Sun-like stars-- has a clear connection to astrobiology. However, in addition to its planet-finding capabilities, the Kepler data may also be used to study other questions of astrobiological interest. In this talk, I will discuss my work on two such ongoing projects: the quantification of the stellar flare rate, which influences planetary habitability through its influence on atmospheric photochemistry and escape; and the detection of anomalous stellar variability as a form of signal-agnostic optical SETI. Both of these lines of research employ machine learning techniques, making them applicable to the current and future large datasets that now dominate the astronomical landscape.